06/02/2026
Can you take HRT if you have Factor V Leiden?
This is a question Dr. Rogers gets from women who have been told they can’t use hormones because of a blood clotting disorder.
His answer?
You have to be careful with the type of hormone therapy.
Oral estrogen is the problem because it goes through the liver, where clotting factors are made.
That’s why Dr. Rogers does not prescribe oral estrogen.
But bioidentical hormone creams are different.
They bypass the liver and do not affect clotting factors the same way oral estrogen can.
So if you have Factor V Leiden, it does not automatically mean you have to suffer through menopause with no options.
You need the right route, the right dose, and a doctor who understands hormone replacement therapy.
Have you been told you can’t take hormones because of clotting risk?