The Jackson Laboratory

06/22/2026

How do we move Alzheimer’s research forward when no single model can fully capture the disease?

At JAX, researchers are bringing together mouse models, cells, and data to better understand Alzheimer’s disease and identify new paths to treatment. By connecting insights across model systems, scientists are building a more complete picture of the disease, and accelerating the search for therapies that can make a difference. 🧠

Read more in this Q&A with JAX Professor Greg Carter:

Five questions with JAX Professor Greg Carter

06/21/2026

Today is The Longest Day! 💜 🧠

Celebrated on the summer solstice each year, the day's abundance of light symbolizes hope, community, and the drive to end Alzheimer's disease. Advocates around the world use this day to do what they love to raise awareness, from hiking and biking to knitting and gaming.

JAX researchers and employees have been participating in The Longest Day for years to show their commitment to ending Alzheimer's.

At JAX, we are closer than ever to changing the future of Alzheimer's disease. Researchers here are pioneering new approaches that aren't possible anywhere else; they're pushing beyond the limits of traditional Alzheimer's research to better understand the disease, uncover new therapeutic targets, and accelerate the path to effective treatments.

This Longest Day, we honor everyone working toward a future without Alzheimer's and related dementias.

06/19/2026

We're excited to announce a new partnership between The Jackson Laboratory and The France Foundation to expand jointly accredited continuing education opportunities for physician assistants, strengthening access to precision medicine learning across the healthcare workforce.

The partnership enables JAX to offer education that better reflects how care is delivered in today’s healthcare environments. By combining JAX’s expertise in genomics and precision medicine with The France Foundation’s longstanding experience developing accredited education for multidisciplinary audiences, the collaboration creates new opportunities to reach clinicians across specialties and practice settings.

Through a new partnership with The France Foundation, JAX is broadening continuing education and strengthening collaborative care nationwide.

06/17/2026

JAX scientists are helping answer some of the most important questions about our brain health.

Genes, proteins and pathways changing in the eye are similar in both the early stages of glaucoma and Alzheimer’s disease, so JAX scientists have been taking an extra look as well as creating a next-generation brain atlas to map the cells, genes and lipids of our brains.

Read all about it in Aging & Neuro from the latest issue of Search: https://go.jax.org/2e6uqf

06/16/2026

Aging is inevitable. But how we age isn’t.

At JAX, scientists are working to understand why some people stay healthier longer and how we can extend not just life, but healthy life: https://go.jax.org/GoodYears

06/15/2026

"It just feels like we're closer than we ever have been. The more of these gaps that we can fill in, the faster we're going to get to a real disease - modifying therapy.” - Kristen O'Connell, Alzheimer's researcher at JAX

By studying lipids, the molecules that help keep brain cells connected, O'Connell is uncovering how memory breaks down over time and how to preserve it.

To O'Connell this work is deeply personal and more than just research. Her grandmother, who supported her early interest in science, lived with Alzheimer’s for nearly 20 years before passing away in 2014. Watching her symptoms increase over time left a lasting impression on O’Connell, and has a big influence on the research she conducts today.

Learn more about this work and how O'Connell hopes to fill critical gaps in our understanding of Alzheimer's disease in the next five to 10 years:

By studying lipids, Kristen O’Connell is uncovering how memory breaks down over time and how to preserve it.

06/13/2026

JAX scientists are identifying immune signatures associated with healthy aging versus decline to inform approaches to disease prevention in older adults.

Read Aging & Systems Immunology in the latest issue of Search: https://go.jax.org/lpykl9

Ucar’s team hopes that by identifying the baseline immune features (biomarkers) present before vaccination, they can predict whether someone will respond well to a vaccine — or whether they might respond better to one formulation
over another.

These insights support the emerging field of precision vaccinology, which aims to tailor vaccine strategies to individual immune profiles.

The long-term goal is to identify immune signatures associated with healthy aging versus immune decline — knowledge that could inform not only vaccination strategies but broader approaches to disease prevention in older adults.

06/11/2026

Thirty-nine curious, high-achieving students arrived on JAX’s campuses in Bar Harbor, Maine, Farmington, Conn., and New York, N.Y. to pursue 10 weeks of hands-on research this summer.

Summer Student Program and JAX-NYSCF Collaborative Summer Science Internship welcome the next generation of scientists.