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CHAI's mission is to save lives and improve health outcomes in low- and middle-income countries by enabling the government and private sector to strengthen and sustain quality health systems.

10/29/2026

Our 2025 Annual Report is out now.

It was one of the hardest years global health has faced. Foreign aid fell by 23 percent, the largest annual decline ever recorded, and governments were suddenly being asked to do more with much less.

CHAI responded with Technical Support Units, advisers supporting ministries of health in 19 countries. In five countries alone, this work saw nearly US$70 million in funding raised or reallocated in less than a year. Billions of dollars are gone from the global health system, and domestic financing alone won’t fill that gap in the short-term. But the examples we share in this report reflect something we noticed across the countries with which we have partnered: governments stepping up, making hard decisions, and finding more in their own budgets.

Read the report: https://ow.ly/g6tF51023Ko

10/28/2026

Every quarter, 22,000+ Village Health Workers across Zimbabwe wait for one message: “You’ve been paid.”

They connect communities to clinics, support mothers and children, and power HIV, TB, and malaria programs. But for years, their payments depended on records scattered across partner systems. By 2024, 1 in 4 payments was being rejected.

Now Zimbabwe runs VHW payments itself.
📉 Payment rejections: 25% → under 5%
📉 Cases needing follow-up: ~5,000 → under 20
✅ One national, government-owned VHW Master List
✅ Standard procedures at every level of the health system

When governments own the systems, health workers get paid on time, and communities keep getting care. 🇿🇼

Read the full story: https://ow.ly/laaw5100fYY

This work was led by Zimbabwe's Ministry of Health and Child Care, with catalytic investment from Project BIRCH, an initiative of The Global Fund, and technical assistance from CHAI and Africa Frontline First.

10/20/2026

The next decade of TB prevention will look nothing like the last.

New, long-acting injectables, ultra-short-course TPT, and TB vaccines could reach low- and middle-income countries within the next five years if approved. What could this wave of new tools mean for their future TB prevention portfolio?

CHAI’s new toolkit puts existing and pipeline options side by side, with timelines, target populations, and the open questions still ahead.

https://ow.ly/cNQ850ZYuyZ

The Global Fund, World Health Organization (WHO), Gates Foundation, Gavi, the Vaccine Alliance, Treatment Action Group (TAG)

10/19/2026

It’s International Lead Poisoning Prevention Week

About 1 in 3 children worldwide have blood lead levels above the threshold set by the World Health Organization. Yet in many countries, testing remains out of reach because current methods are lab-based, costly, and centralized.

What would it take to make testing more accessible and routine? CHAI and Renaissance Philanthropy are hosting a webinar on Thursday, Oct. 29, 10:00 a.m. EDT To discuss just that.

Building on the Target Product Profile published earlier this year, Catherine Karr, Phillip Erbele, Sumi Mehta, and Robbie Barbero will discuss what the next generation of blood lead tests needs to deliver. We'll also share details of an open call for innovators ready to help build them.

Whether you're a test developer, researcher, funder, or public health leader, we'd love to have you in the conversation.

🔗 Register here: https://ow.ly/EsqP50ZZ5qe

Renaissance Philanthropy, Vital Strategies, Partnership for a Lead-Free Future , University of Washington

10/08/2026

For more than 13 years, Maryam Yakub has made her living with a needle and thread. As her near vision faded, that livelihood got harder. She relied on her children to thread the needle in her sewing machine—if they weren’t there, her work would have to stop until they came back.

"Before I could not thread the needle in my sewing machine, but now I can do it very well."

Maryam received a free pair of reading glasses through Jigi Bola 2.0, Nigeria's presidential initiative to bring presbyopia care into the primary health care system. Presbyopia is the age-related loss of near vision. It affects an estimated 25 million Nigerians, and the solution, a pair of reading glasses, costs about US$1 to manufacture.

In its first year, Jigi Bola 2.0:
→ Screened 1.5 million Nigerians
→ Provided 1.3 million people with free eyeglasses across 16 states
→ Reached people who had never had glasses before. Two-thirds of recipients received their first-ever pair, and more than half were women.

CHAI works with the National Eye, Ear, and Sensory Functions Health Programme to train primary health care workers, manage eyeglasses supply chains, build community demand, and monitor dispensing. The program is now expanding from 10 to 21 states, with a goal of reaching 5 million Nigerians by 2027.

This , Maryam's story is a reminder of what happens when vision care reaches the last mile. https://ow.ly/WehU50ZW3hY

Thank you to the Federal Ministry of Health and Social Welfare, National Eye, Ear and Sensory Functions Health Programme, Livelihood Impact Fund, RestoringVision, Christian-Health Association-of Nigeria, and Vital Strategies for their partnership.

10/02/2026

COVID-19 exposed the oxygen gap. Six years later, governments and partners have built a system that now reaches millions.

579+ oxygen plants. 165 liquid oxygen storage systems. Hospitals that once ran out of oxygen now have it.

🇪🇹 Ethiopia: oxygen plants went from 3 to 55.
🇺🇬 Uganda: oxygen availability went from 38% to almost 100% across 50+ districts.
🇰🇪🇹🇿 Kenya and Tanzania: a regional oxygen production network set to triple supply across East and Southern Africa.

This system was built by ministries of health and supported by partners including Gates Foundation, The ELMA Foundation, Unitaid, The Global Fund, Helmsley Charitable Trust, MedAccess, PATH, and others.

10/02/2026

In Uganda today, almost every child who needs oxygen gets it, across the country in 50+ districts.

That wasn’t always the case: oxygen availability used to sit at only 38%.

The problem was facilities would use cylinders until empty, then wait days for those cylinders to be collected and refilled—in the meantime, they’d run out of supply.

CHAI piloted “Exchange on Delivery” in Jinja and Mubende through the MOXI program, funded by Gates Foundation and The ELMA Foundation.

The fix was surprisingly simple: swap out the empty cylinder for a full one at the point of delivery = no more long waits for refills.

In 2025, Ministry of Health- Uganda made it national policy, and the Ministry and CHAI won the Global Health Supply Chain Summit Grand Prize in Kigali.

On , this is a model we want to see replicated.

10/01/2026

A year ago, a deal was announced to bring a breakthrough HIV prevention shot, which cost US$28,000 per person per year, to the world's poorest countries for only US$40.

On the sidelines of UNGA last week, CHAI CEO Neil Buddy Shah joined Michael Igoe for a live recording of Devex's Theory of Change podcast. They discussed how CHAI, Dr. Reddy's Laboratories Ltd., Wits RHI, and Unitaid came together on lenacapavir, a twice-yearly injection that is 99% effective at preventing HIV. They also talked about what comes next.

In the conversation:
➡️ How market shaping balances sustainable business models with the lowest possible price
➡️ What it would take to end HIV as an epidemic in Africa within a decade
➡️ Why low- and middle-income countries may be the first to build world-class AI clinical assistants

Watch now: https://ow.ly/Cc3H50ZTF6B

09/29/2026

Ghana's malnutrition program had stalled — trained health workers had retired, supply chains were inconsistent, and there was no plan to sustain it without donors. Today, we are helping rebuild it as a system Ghana can own, fund, and run for the long term.

Alongside the Ghana Health Service, the Ministry of Health, Ghana, and the Eleanor Crook Foundation, that means strengthening the supply chains, training, and financing behind two lifesaving interventions: ready-to-use therapeutic food (RUTF) for severely wasted children, and multiple micronutrient supplements (MMS) for pregnant women.

More than 20,000 children have been treated for severe wasting, and nearly 10,000 pregnant women have received MMS. The next step: bringing both under Ghana's National Health Insurance Scheme (NHIS) for lasting, government-led financing.

Hear from CHAI's Dr. Maame Asamoa-Amoakohene on what full government ownership looks like.

Full story on Devex: https://ow.ly/k45Y50ZSFMj

09/25/2026

Exposure to lead directly affects a child's brain development, and the damage it does in those early years can't be undone. An estimated 1 in 3 children worldwide is living with blood lead levels high enough to substantially affect how they learn, grow, and thrive, often without anyone knowing.

The good news is there is real momentum in this fight. At this week’s Clinton Global Initiative Annual Meeting, leaders from government, philanthropy, and civil society joined a community roundtable on ending childhood lead poisoning, pointing to progress under the Partnership for a Lead-Free Future: the coalition has mobilized US$500 million toward ending childhood lead poisoning by 2040. From the main stage, former USAID Administrator Samantha Power echoed that momentum, urging leaders to "do what is required together to finish the job."

Among the efforts underway: a joint program between CHAI and Renaissance Philanthropy to close the diagnostics gap, working toward an affordable field-ready blood lead test that trained providers can use with no lab required.

We know how to solve this. Now it's a matter of building and scaling the tools to reach every child at risk — before more of their potential is lost to a fixable problem.

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