Awaken Integrative Wellness Clinic

Call Directions Website Contact the practice

Awaken Integrative Wellness Clinic Dr. Carmen Call, DAcCHM, LAc. Providing Holistic and Integrative Healthcare to the San Francisco Bay Area. Find out more: AwakenSF.com

Specializing in Eczema, Allergies, Mast Cell Activation Syndrome (MCAS), Alpha gal, Autoimmunity & Chronic Illness.

Glad the pieces are being put together! Mast Cell Activation Syndrome is behind the majority of chronic diseases.
10/08/2026

Glad the pieces are being put together! Mast Cell Activation Syndrome is behind the majority of chronic diseases.

Scientists are increasingly investigating mast cells as an important contributor to endometriosis pain. Mast cells are immune cells best known for their role in allergies, but they also regulate inflammation and interact closely with the nervous system.

Studies examining endometriosis tissue have found increased numbers of activated mast cells within lesions, particularly in painful deep infiltrating endometriosis.

One human tissue study reported that roughly 89% of mast cells within endometriotic lesions showed signs of degranulation, meaning they were actively releasing stored inflammatory compounds. Researchers have also observed activated mast cells located extremely close—within about 25 micrometers—of nerve fibers in endometriosis lesions.

This close relationship between mast cells and nerves could help explain how inflammation contributes to persistent pain. When mast cells become activated, they can release histamine, tryptase, cytokines and other signaling molecules that can stimulate or sensitize nearby pain-sensing nerves, making them respond more strongly to normally tolerable signals. Estrogen may further influence mast-cell activity and the inflammatory environment surrounding endometriosis lesions.

Researchers therefore propose a neuroimmune feedback loop, where mast-cell inflammation increases nerve sensitivity and nerve signaling can further influence local immune activity.

10/06/2026
10/05/2026

It should be a simple fix with TCM acupuncture and herbs. However, once the immune system becomes too dysregulated we must resolve the Biao (the branch - acute MCAS symptoms with 95% permanent remission through SAAT) before we can resolve the Ben (the root - underlying constitutional or organ imbalances driving the mast cells to overreact). The body always wants to heal. We must approach it with the proper treatments. I’m so grateful for SAAT!

I never thought this day would arrive. I’m so grateful awareness of mold/fungal illness is now “mainstream”. I barely su...
09/26/2026

I never thought this day would arrive. I’m so grateful awareness of mold/fungal illness is now “mainstream”. I barely survived mold illness. My chronic illness started when I lived in a moldy home at 20 years old. I searched for my diagnosis and treatment to heal it for 22 years. It took me 22 years, 4 years beyond my medical degree, to learn it was MCAS and finally heal. Mold causes MCAS. COVID and vaccines also are known to cause MCAS. Any stressor can trigger it. Immune systems are becoming significantly overwhelmed and triggered. I see it every day in my clinic. Patients that come to me for traditional acupuncture, not even seeking SAAT, also have autoimmune issues and/or food allergies. You can’t have autoimmunity or cancer without having MCAS first. Of course there is more mold/fungal illness now. Our immune systems are treading water. As long as you’re not currently living in mold, SAAT and Auricular Medicine can put it all into remission. I am proof and 95+% of my patients are proof.

🚨 Federal officials have now acknowledged what thousands of families have been living with for years—mold-related disease is spreading faster than the medical system can name it, diagnose it, or treat it.

At a Sept. 18 HHS Mold Surveillance Roundtable, Health Secretary Robert F. Kennedy Jr. said a growing number of U.S. adults and children are sick from mold and other fungi, often for years, while doctors miss the cause.

“This will be the beginning of an effort to educate the public, to educate physicians,” Kennedy said, “so that everybody who’s affected by this disease can get some help.”

The human cost is already on the record.

CDC figures cited at the event include about 7,300 fungal-disease deaths a year, tens to hundreds of thousands of hospitalizations, and millions of outpatient visits, with invasive mold infections killing 50 to 70 percent of those who develop them.

Officials warned those numbers almost certainly understate the true burden, because there is still no comprehensive national surveillance for all fungal diseases and most medical schools still do not teach physicians how to find them.

Kennedy made the stakes personal.

He once lived in a house so contaminated it had to be torn down; nearly all of his children were affected, his wife was “very, very badly affected in many ways that doctors couldn’t understand,” and one son saw 89 doctors before a chronic mold infection was identified.

“I worry about the many other Americans who may not have found the solution,” he said—people living with brain fog and “all of the other crazy stuff that this does to you every day.”

CDC Director Erica Schwartz said clinicians must start asking whether invasive mold or another severe fungal infection is why a patient is not getting better.

The agency pledged more than $1.5 million to the patient group MyCARE for education, along with millions more for research and for state and local lab and surveillance capacity.

Doctors who treat these patients say the waiting rooms are filling with young mothers and children.

Blood tests can detect mold antibodies, they report, but recovery does not begin until the source is found and removed.

Engineered wood, prior water damage, pesticide load, immune disruption, and even electromagnetic exposure were all raised as possible reasons the problem is accelerating.

On autism, the reporting is stark but not settled.

Research has not proven that mold causes autism, yet some studies have found elevated mycotoxins and mold-related antibodies in autistic children, and clinicians say mycotoxins can hit the same already-vulnerable systems harder.

That is a warning light, not a closed case.

Kennedy’s question now hangs over federal health policy: What is causing this explosion, and how do we stop it?

For families still bouncing between specialists with no diagnosis, the roundtable was less a conclusion than an admission that the system has been looking in the wrong places.

08/17/2026

A review published in the International Journal of Molecular Sciences discussed a study of 400 people with mastocytosis, a condition involving abnormal accumulation of mast cells. Among them, 15 also had autism (3.75%). Using the general-population autism prevalence cited at the time (about 1 in 180), the authors described this as approximately 6.75 times higher. Importantly, this was an observed association and does not show that mast-cell activation causes autism.

Researchers have proposed several possible biological connections between mast cells, inflammation, and ASD. Activated mast cells can release histamine, cytokines, tryptase and other inflammatory substances that may affect the blood-brain barrier and interact with microglia, the brain's resident immune cells. The review discusses the possibility that these processes contribute to neuroinflammation in a subset of people with ASD. However, the authors conclude that the relationship between mast cells and autism remains controversial and poorly understood, and more research is needed to determine whether mast-cell abnormalities influence ASD development or symptoms.

Research published in 2024.
07/07/2026

Research published in 2024.

Emerging research suggests a notable association between Autism Spectrum Disorder (ASD), mast cell dysfunction, and broader immune dysregulation. Some clinical studies of children with mastocytosis—a rare disorder involving abnormal mast cell accumulation or activation—have reported higher rates of ASD than those seen in the general population.

In addition, food allergies and immune-related problems appear to be more common in some autistic children. Mast cells are immune cells concentrated in the gut, skin, and near the blood-brain barrier, where they release substances such as histamine and inflammatory cytokines.

Researchers are investigating whether excessive or poorly regulated mast cell activation, triggered by factors such as stress, infection, or environmental exposures, could contribute to inflammation and influence neurological symptoms in susceptible individuals. However, these findings show an association and do not establish mast cell activation as a cause of autism.

Mast cell activation may also overlap with or worsen challenges experienced by some autistic individuals. Excessive mediator release can be associated with gastrointestinal pain, bloating, food intolerance, flushing, hives, headaches, sleep disturbance, brain fog, anxiety, irritability, and changes in attention or activity levels.

PMCID: PMC10932299 PMID: 38473898

Demodex Overgrowth. It is the cause of everything from folliculitis to rosacea, recurring styes and dry eyes. I have com...
07/02/2026

Demodex Overgrowth. It is the cause of everything from folliculitis to rosacea, recurring styes and dry eyes. I have come to recently suspect a strong correlation with eczema and alopecia as well. It is very common specifically in immunocompromised individuals - due to MCAS, autoimmunity, mold exposure, antibiotic usage/medications, COVID/viruses and vaccine injury. The older the patient, the more likely they have the overgrowth. I have had patients in their 30s with demodex overgrowth as well.

Demodex mites are among the most prevalent human parasites. While commonly found on healthy individuals, an overpopulation of this arachnid resident of human skin triggers demodicosis, a neglected yet widely prevalent disease with considerable skin ...

Address

630 8th Street
San Francisco, CA
94103

Alerts

Be the first to know and let us send you an email when Awaken Integrative Wellness Clinic posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Contact The Practice

Send a message to Awaken Integrative Wellness Clinic:

Shortcuts

Share