Perspectum

Perspectum Innovating medical imaging in Oxford - where tradition meets technology. AI-driven, patient-focused, advancing healthcare.

Perspectum is a medical diagnostics company, and developer of LiverMultiScan, a non-invasive MRI based test for liver disease. Follow the link to our website to discover more about advanced liver visualisation

We hope to use this page to keep in touch with people interested in us, as well as the wider liver community.

If the same fibrosis stage can coexist with different levels of disease activity, the starting question is not simply wh...
30/07/2026

If the same fibrosis stage can coexist with different levels of disease activity, the starting question is not simply which test to run. It is what we need to measure.

One liver can raise three distinct questions:

How much fat is present?

How much structural damage has accumulated?

How much disease activity is present... and is it changing?

No single measurement answers all three.

MRI-PDFF quantifies liver fat. Fibrosis assessment characterizes accumulated structural burden and long-term risk. cT1 provides a quantitative measure of disease activity, adding complementary information about what is happening now in the liver as well as longitudinal tissue change.

These are not competing answers to the same question. They describe different dimensions of the same liver, and together can provide a more complete picture.

The question should determine the measurement.

Learn more about LiverMultiScan: https://perspectum.com/products/livermultiscan/

Two patients. Similar fibrosis stage. Different levels of disease activity.Fibrosis tells us how much structural damage ...
21/07/2026

Two patients. Similar fibrosis stage. Different levels of disease activity.

Fibrosis tells us how much structural damage has accumulated. It remains essential for staging, prognosis and long-term risk assessment.

But fibrosis burden alone does not fully describe what is happening in the liver now.

Disease activity arises from interacting biological processes including inflammation, cellular injury and active fibrogenesis. The downstream tissue consequences of these processes can differ substantially between patients with similar fibrosis.

That is why different biomarkers answer different clinical questions.

Fibrosis assessment characterizes accumulated structural burden. MRI-PDFF quantifies the amount of fat. cT1 complements these by measuring the level of liver disease activity.

Together, structural assessment and quantitative tissue characterization can provide a more complete picture of MASLD and how it changes during treatment.

Learn more: https://perspectum.com/products/livermultiscan/

Not all body fat carries the same risk, and the dangerous kind doesn't show up on the scales.In 75,331 UK Biobank partic...
15/07/2026

Not all body fat carries the same risk, and the dangerous kind doesn't show up on the scales.

In 75,331 UK Biobank participants, MRI-measured visceral fat predicted type 2 diabetes, liver, cardiovascular and kidney events beyond BMI. And one MRI slice matched a full abdominal 3D scan.

Standard checks can miss liver disease in children. Imaging can reveal it.In Mexico's METCOG cohort, ~1 in 7 children sc...
15/07/2026

Standard checks can miss liver disease in children. Imaging can reveal it.

In Mexico's METCOG cohort, ~1 in 7 children scanned showed signs of MASLD, often without symptoms.

Observational study. Luis presents at ICO 2026: https://icocongress.com/programme-overview/

159 vs 20.The estimated number you'd treat with a weight-loss medication to delay one death, before and after adding two...
15/07/2026

159 vs 20.

The estimated number you'd treat with a weight-loss medication to delay one death, before and after adding two MRI measurements to the decision.

23,087 UK Biobank participants. Modeled on published trial data.

Our ICO 2026 poster.

We're heading to Mexico City. 🇲🇽Perspectum is at the International Congress on Obesity, 15–17 July.BMI alone doesn't tel...
08/07/2026

We're heading to Mexico City. 🇲🇽

Perspectum is at the International Congress on Obesity, 15–17 July.

BMI alone doesn't tell you where the risk sits. The liver, heart, pancreas and muscle do. We'll be sharing new quantitative MRI research on sharpening risk stratification in obesity.

Find us there.

Primary sclerosing cholangitis (PSC) is a rare, progressive liver disease, and one of the hardest parts of caring for pe...
02/07/2026

Primary sclerosing cholangitis (PSC) is a rare, progressive liver disease, and one of the hardest parts of caring for people who live with it is knowing how the disease will progress.

A new publication in JHEP Reports shows that a novel score (qmAOM) combining quantitative MRCP with the Amsterdam Oxford model outperforms currently used scores in the prediction of long-term, event-free survival in patients with PSC, with stable accuracy over a 10-year horizon.

The study, led by Tim Middelburg [tag co-authors] and colleagues, also established the first reference range for quantitative MRCP metrics in PSC — a step toward more consistent assessment across hospitals and patients.

A meaningful step forward for the PSC community.
📄 Read the paper: https://www.jhep-reports.eu/article/S2589-5559(26)00163-1/fulltext

This Armed Forces Week, we're proud to recognise the veterans and reservists across our team, and to reaffirm our commit...
25/06/2026

This Armed Forces Week, we're proud to recognise the veterans and reservists across our team, and to reaffirm our commitment as a signatory of the Armed Forces Covenant.

Signing the Covenant is a promise: that those who serve, have served, and their families are treated fairly and are never disadvantaged for their service. It's a commitment we carry into how we recruit, support and work together every day.

Learn more about the Armed Forces Covenant: armedforcescovenant.gov.uk

Address

Gemini One 5520 John Smith Drive
Oxford
OX42LL

Opening Hours

Monday 9am - 5pm
Tuesday 9am - 5pm
Wednesday 9am - 5pm
Thursday 9am - 5pm
Friday 9am - 5pm

Telephone

+44 (0)1865 655343

Website

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