10/28/2026
Duke researchers discovered that antibodies produced naturally inside tumors after immunotherapy can recognize cancer cells. By engineering one into CAR T cells, they targeted both tumor cells and cancer-promoting immune cells, revealing a potential new source for future cancer therapies. Click the link to learn more.
https://duke.is/5/p54z
Duke Health
Meyerhoff et al. identify tumor-infiltrating plasma cells as a source of antibodies with therapeutic potential. Their lead antibody, PC-1, recognizes citrullinated antigens on cancer and tumor-promoting myeloid cells and can be repurposed to guide CAR T cell therapy.