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Monday 8:30am - 5:30pm Tuesday 8:30am - 5:30pm Wednesday 8:30am - 5:30pm Thursday 8:30am - 5:30pm Friday 8:30am - 5:30pm

Patient-Centered Outcomes Research Institute - PCORI

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Patient-Centered Outcomes Research Institute - PCORI

PCORI funds patient-centered comparative clinical effectiveness research (CER).

06/19/2026

Knee and hip osteoarthritis (OA) is a chronic condition that causes pain and stiffness. While joint replacement surgery may help, it is not a viable option for everyone.

Through a PCORI-funded study consisting of 2 patient-centered CER studies, a research team compared 3 ways to make OA treatment decisions:
1️⃣ A custom decision support report alone
2️⃣ A custom decision report plus online group health coaching sessions
3️⃣ Usual care

Read more about the study: https://pcori.me/4omfkWH

06/18/2026

PCORI is seeking public input on draft research questions for an upcoming systematic review: Surgical Treatment of Adults With Degenerative Lumbar Spinal Stenosis.

Your feedback can help ensure the final review better reflects the perspectives of patients, caregivers and the broader healthcare community.

Learn more and submit your input: https://pcori.me/4o4VsYN

06/17/2026

Deadline Tomorrow: Public Comments on the Draft Update of PCORI’s Methodology Standards❗

As part of its ongoing efforts to advance patient-centered CER, PCORI is seeking public comment on a comprehensive update to its Methodology Standards for patient-centered CER.

Take advantage of this opportunity to help inform the future conduct of patient-centered CER! https://pcori.me/4tiK65r

06/16/2026

A PCORI-funded randomized clinical trial compared two school-based programs for preventing cavities:

1️⃣ Standard program: sealant and a fluoride varnish
2️⃣ New program: topical silver diamine fluoride and a fluoride varnish

The new program took less time than the standard program and could be performed effectively by school nurses. Study results showed that both programs worked about the same in controlling tooth decay and preventing new cavities.

Read more: https://pcori.me/4uzTG4b

06/15/2026

Check out the Engagement in Health Research Literature Explorer, a streamlined resource with more than 2,000 peer-reviewed citations on patient engagement in health research.

With the Literature Explorer, you can find relevant content by searching within different types of articles, such as:
◽ Empirical studies of engagement
◽ Descriptions of real-world engagement practices
◽ Expert commentaries and perspectives
◽ Systematic and other reviews

Learn more: https://pcori.me/3mM9ZuH

06/12/2026

The latest edition of PCORI’s Emerging Health Care Innovation Brief highlights FDA approval for treatments targeting advanced, unresectable or metastatic bile duct (passage) cancer and relapsing-remitting multiple sclerosis.

Other topics to watch:
◼️ Elegrobart, an under-the-skin, self-administered treatment for thyroid eye disease.
◼️ Taletrectinib, a tyrosine kinase inhibitor designed to treat a rare, aggressive non-small cell lung cancer.

Explore emerging topics: https://pcori.me/4okrosi

06/11/2026

Closing Next Week: Public Comments on the Draft Update of PCORI’s Methodology Standards

This update includes a change to the overall structure of the Standards, major revisions to the wording of most Standards and new Standards in five areas:
◼️ Artificial intelligence
◼️ Patient-centered burdens and economic outcomes
◼️ Health communications
◼️ Hybrid effectiveness-implementation studies
◼️ Real-world data

Take advantage of this opportunity to help shape the conduct of patient-centered CER! https://pcori.me/4tiK65r

06/10/2026

Mark your calendar! 📆

The 2026 PCORI Annual Meeting will take place Oct. 19-20 at the Marriott Marquis in downtown Washington, D.C.

Join hundreds of professionals from across the nation at one of the most engaging events in healthcare. Watch for registration details in the coming weeks! https://pcori.me/4fW2BW0

06/09/2026

Older adults with complex healthcare needs — such as those living with multiple chronic conditions and functional limitations — often face gaps in care coordination, which could affect their health outcomes.

A PCORI-funded randomized controlled trial is comparing 2 approaches to determine which is more effective for older adults:

1️⃣ Structured annual wellness visits (AWVs) in primary care practice

2️⃣ Structured AWVs enhanced with Geriatrics Resources for the Assessment and Care of Elders (GRACE), an interprofessional care delivery model that includes facilitating co-management between the GRACE and primary care teams

Read more: https://pcori.me/40oszf8

06/08/2026

A final report is now available for the systematic review on Mindfulness-Based Interventions for Well-Being and Mental Health in Children and Adolescents.

This review examines current evidence on mindfulness-based interventions to help inform clinical practice guidance and support decision making by physicians, patients and caregivers. https://pcori.me/3Qbivod

Address

1333 New Hampshire Avenue Suite 1200
Washington D.C., DC
20036

Opening Hours

Monday	8:30am - 5:30pm
Tuesday	8:30am - 5:30pm
Wednesday	8:30am - 5:30pm
Thursday	8:30am - 5:30pm
Friday	8:30am - 5:30pm

Website

http://www.pcori.org/

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