Dra Vania Ligia

11/08/2026

A queda da patente da semaglutida reduziu preços, mas canetas emagrecedoras ainda pesam no orçamento de muitos brasileiros.

11/08/2026

Childhood trauma physically alters how cells produce energy, forcing mitochondria into a state of chronic, damaging hypermetabolism, new study shows.

How does childhood trauma translate into lifelong physical and mental illness? A pioneering UCLA study published in Biological Psychiatry offers a compelling cellular explanation: early-life adversity fundamentally alters mitochondria, the powerhouses of our cells.

By conducting stress tests on live immune cells from adult volunteers, researchers discovered that those who experienced childhood abuse or neglect had mitochondria with an elevated capacity to produce energy. While this hyperactive state—known as hypermetabolism—helps cells quickly cope with immediate stress in the short term, running this cellular engine constantly in the red zone over decades can prematurely wear out the cells, accelerating age-related diseases.

Crucially, the study shows that different types of trauma leave distinct biological scars. While experiences of threat and abuse prepare cells to brace for future stress by altering routine energy demands, experiences of deprivation and neglect lead to highly inefficient energy production. This cellular dysfunction suggests that trauma is not a monolithic experience, and its biological footprint is highly nuanced. By revealing these distinct cellular pathways, researchers hope to design highly targeted early interventions that can protect mitochondrial health and break the link between early hardship and chronic adult disease.

source: Cleveland, S., Carroll, J. E., Montoya, A. K., Cha, L., Stiles, L., & Sumner, J. A. (2026). Early-Life Adversity and Mitochondrial Function: Comparing Cumulative Risk and Dimensional Models of Adversity. Biological Psychiatry.

11/08/2026

Ela influencia humor, memória, fertilidade, sono e vida sexual; conheça sintomas que passam despercebidos e os principais problemas que atingem a glândula.

📖 Link da matéria nos comentários

09/08/2026

🙏🏻🩵 feliz domingo feliz dia dos pais

02/08/2026

26/07/2026

👩🏻‍🦱💙🙏🏻 parabéns

> *Fabiana, filha amada!*
> No dia que você nasceu, meu mundo ficou mais bonito.
> Ver você crescer é meu maior presente.
> Te amo hoje e em todos os dias da sua vida.
> *Feliz aniversário!*

24/07/2026

America's falling birth rate is being driven entirely by left-leaning voters, new data shows — and education was consistently linked to having fewer children.

A groundbreaking study published in Scientific Reports reveals that the ongoing decline in U.S. birth rates is not a uniform trend across the population, but is instead heavily concentrated among left-leaning Americans.

By analyzing decades of data from the General Social Survey, researchers Martin Fieder and Susanne Huber discovered that while conservative Americans have consistently maintained birth rates near or slightly above the replacement level of 2.1 children per woman, fertility among liberals has plummeted.

This divergence first emerged with generations born in the mid-1940s—coinciding with the advent of modern contraception—and has widened significantly in recent decades, primarily driven by demographic shifts among White Americans.

Because political orientations are highly heritable and often passed down from parents to children, this stark fertility gap could have profound implications for the future ideological makeup of the United States. While lifestyle factors like higher education levels tend to lower birth rates across the board, frequent religious attendance and conservative beliefs continue to support larger family sizes. The researchers suggest that the "rightward shift" currently observed in various political climates globally may be less about persuasion and more about demographic reality, as liberal populations increasingly opt for smaller families while conservative populations sustain their numbers.

source: Fieder, M., & Huber, S. (2026). Falling Fertility on the Left as Key Driver of US Birth Decline. Scientific Reports.

24/07/2026

Muito antes de uma doença aparecer, milhões de proteínas trabalham continuamente para manter nossas células em equilíbrio. Entre elas estão as **proteínas chaperonas**, verdadeiras "guardiãs moleculares".

A função delas é garantir que outras proteínas sejam produzidas e dobradas da maneira correta. Quando esse processo falha, proteínas defeituosas podem se acumular, favorecendo doenças neurodegenerativas, inflamatórias e até alguns tipos de câncer.

O mais interessante é que essas mesmas proteínas podem ter um papel duplo: enquanto ajudam a proteger células saudáveis, alguns tumores conseguem "se aproveitar" delas para sobreviver e crescer. É justamente por isso que as chaperonas se tornaram alvo de pesquisas em busca de novos tratamentos contra o câncer.

A medicina avança quando compreendemos que, muitas vezes, as maiores batalhas acontecem em uma escala invisível aos nossos olhos.

🔬 Conhecer esses mecanismos é o primeiro passo para desenvolver terapias cada vez mais precisas e eficazes.

💬 Você já tinha ouvido falar nas proteínas chaperonas? Conte nos comentários.

Dr. Natalício Kern Filho - Médico Hematologista, Oncohematologista e Hemoterapeuta RQE10.418 | RQE 10.419, Medicina Interna | RQE 10.403. Preceptor Sírio Libanês CRM RS18819
Agende sua consulta📲(51) 993500536 - NH (51)39393628 | (51) 99354.3495 Whatsapp Caxias do Sul (54)999297173 WhatsAp - Atendimento on-line (51)993320903 WhatsApp